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韦祖壮 香港最精准十码教师
药物化学,化学生物学
研究方向: 药物化学,化学生物学
岗  位: 香港最精准十码教师
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基本情况

韦祖壮,男,博士,毕业于中山大学,现任香港最精准十码教师。主要研究方向为药物化学,化学生物学等。近年来在Eur. J. Med. Chem.、Chem. Commun.、Bioorgan. Chem.Int. J. Mol. Sci.、Molecules等国际学术期刊公开发表SCI论文5篇。目前主持香港最精准十码****科研启动项目(自然科学)1项。



教育与工作经历





教学工作





科研方向与业绩

发表的论文:

1. Zu-Zhuang Wei1, Qi-Pin Qin1, Ting Meng, Cai-Xing Deng, Hong Liang, Zhen-Feng Chen*. 5-Bromo-oxoisoaporphine platinum(II) complexes exhibit tumor cell cytotoxcicity via inhibition of telomerase activity and disruption of c-myc G-quadruplex DNA and mitochondrial functions. Eur. J. Med. Chem. 2018,145, 360-369.

2. Qi-Pin Qin1*, Zu-Zhuang Wei1, Zhen-Feng Wang, Xiao-Ling Huang, Ming-Xiong Tan, Hua-Hong Zou, Hong Liang*. Imaging and therapeutic applications of Zn(II)-cryptolepine–curcumin molecular probes in cell apoptosis detection and photodynamic therapy. Chem. Commun. 2020, 56, 3999-4002.

3. Zu-Zhuang Wei, Xiaomin Lin, Siyi Wang, Jiahui Zhang, Dongsheng Ji, Xue Gong, Zhi-Shu Huang, Bing Shu*, Ding Li*. Syntheses and evaluation of acridone derivatives as anticancer agents targeting Kras promoter i-motif structure. Bioorgan. Chem. 2023, 136, 106526, https://doi.org/10.1016/j.bioorg.2023.106526.

4. Zu-Zhuang Wei, Bo-Bo Liu, Xiao-Min Lin, Jing Wang, Zhi-Shu Huang, Ding Li*. Development of a smart fluorescent probe specifically interacting with c-myc i-motif. Int. J. Mol. Sci. 2022, 23(7), 3872, https://doi.org/10.3390/ijms23073872.

5. Zu-Zhuang Wei1, Qi-Pin Qin1, Jia-Nian Chen, Zhen-Feng Chen*. Oxoisoaporphine as potent telomerase inhibitor. Molecules, 2016, 21, 1534, doi:10.3390/molecules21111534.


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